Math  /  Data & Statistics

QuestionShingles is a painful, but not life-threatening, skin rash. A doctor has discovered a new ointment that he believes will be more effective in the treatment of shingles than the current medication. Eight patients are available to participate in the initial trials of this new ointment. It turns out that the new ointment does appear to be effective, but it is more effective for younger patients. A second study is planned, and many more patients are available. Based on the knowledge gained from the first study, which method is best to use in the second study? Use age as the response variable Decide which patients receive the new ointment using a multistage sample Use treatment and control groups and also ensure that the patients in the two groups are similar in terms of age Design the second study in the same way as the first

Studdy Solution

STEP 1

1. The goal is to determine the most effective method for conducting a second study on the new ointment.
2. The effectiveness of the ointment varies with the age of the patients.
3. We have access to a larger pool of patients for the second study.

STEP 2

1. Analyze the effectiveness of using age as the response variable.
2. Evaluate the use of a multistage sample to decide treatment allocation.
3. Assess the use of treatment and control groups with age-matched patients.
4. Consider designing the second study in the same way as the first.

STEP 3

Analyze the effectiveness of using age as the response variable:
- Using age as the response variable is not appropriate because age is not the outcome of interest. The response variable should be the effectiveness of the ointment.

STEP 4

Evaluate the use of a multistage sample to decide treatment allocation:
- A multistage sample involves selecting samples in stages, often using different methods at each stage. This approach is more complex and may not directly address the need for age-matched groups.

STEP 5

Assess the use of treatment and control groups with age-matched patients:
- Using treatment and control groups ensures that any differences in outcomes can be attributed to the ointment rather than other factors. - Ensuring age-matched groups controls for the known variable (age) affecting effectiveness, making this a robust method.

STEP 6

Consider designing the second study in the same way as the first:
- Repeating the first study design may not be optimal since it did not account for age differences, which were found to be significant.
Conclusion: The best method for the second study is to use treatment and control groups and ensure that the patients in the two groups are similar in terms of age. This approach controls for the age variable, which is known to affect the effectiveness of the ointment.

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